We provide, beyond conventional medicine, faster and deeper insight into a wide spectrum of pathologies, enabling faster and more effective interventions. IRIS serves physicians and patients at Stanford, UCSF, Sutter Health, Kaiser Permanente, Dignity Health, and other hospitals across the country. IRIS has helped healthy people and people with cancer, heart disease, dementia, diabetes, intestinal problems, autoimmune diseases, and other conditions. IRIS examines up to 3.2 billion molecules in an individual’s DNA sequence; more than 1,100 species of gut microbes; millions of microbial gene activities; and approximately 900 metabolites. The standard comprehensive metabolite test that doctors order only includes 14 metabolites. IRIS offers the most in-depth functional microbiome analysis.

The IRIS platform integrates all this biochemical information with personal medical records, lifestyle, family history and environmental factors, which is then distilled into practical recommendations. IRIS is relevant to you and your family because it can provide important insights, beyond conventional medicine, that can make a real, positive impact on the quality of your lives. You are unique and IRIS works with you and your healthcare provider(s), based upon your actual data, to help optimize your health and wellness.

(* Names and photos have been changed to protect privacy.)

James has diabetes, aortic aneurysm, gout, and other diseases. He is a cancer survivor and is obese. Jim has been cared for at two of the top 10 hospitals in the nation. He has complex health issues, and his physicians, using the best of conventional medicine, were unable to help him. He experienced sudden loss of energy, making it dangerous and unsafe to drive.  He chose to come to IRIS for help even though he has the means to get the best care possible anywhere else in the world. We did the individual comprehensive test for him.  We were able to provide insights to him and his physicians on why changing certain medications could be helpful, and his medication was changed. We also identified what may be the root causes of his lack of energy and other serious conditions. As a result of our whole genome test, he and his siblings were relieved to learn that his cancer was not due to the inheritance of defective genes.

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Michael has Crohn’s disease, which is a form of inflammatory bowel disease (IBD). He was having bowel movements more than ten times a day. After careful analysis of his entire DNA, lifestyle, and medical history, our experienced medical staff was able to recommended a new drug, and as a result, his doctor changed his prescription. We then educated the patient on how his microbiome and life style impacted his disease. With the the adjustments in medication and life style, he now has just a couple of bowel movements a day. Though his quality of life improved immensely, he still lacks energy. Our functional microbiome test showed that his gut was highly deficient in microbial functionality. Our in-depth metabolite test, which analyzed approximately 900 metabolites, showed his chemical imbalances and how they are associated with various diseases. Both of the functional microbiome and in-depth metabolite tests enable him to take steps to further improve his health.

Betty, a woman with a family history of breast cancer, was concerned because her mother died of the disease. She wanted to understand the science and the testing that was available so she can be proactive in her decisions but she wanted her information to be kept confidential. IRIS was able to explain the science to her and also informed her that a doctor would need to order any genetic test. The other option was to participate in an individualized clinical study where her data would be kept confidential in the company and would not be in her medical records. Recent studies have shown that breast cancer is linked not only to the DNA, but also to the microbiome. A bad microbiome can cause different types of cancer.  A good microbiome plays a positive role in determining the efficacy of treatment.

Obesity or Cancer - Which Is the Bigger Problem? Fitness - Blog - March 14, 2017
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John, a man with heart disease, was facing potential open-heart surgery to correct a problem with aortic enlargement, which can be life threatening. The hospital thought that perhaps this condition was caused by a genetic disease leading to the expansion of the main blood vessel that carries blood from the heart to the rest of the body. We met with the patient’s genetic counselor and we also screened his DNA. We discovered that he did not have the genetic disease. We reviewed the patient’s medical record and talked with the patient in detail about his life style, environment, and family medical history. We explained how the microbiome could impact his heart condition and how our in-depth metabolite test (chemical signatures) could be helpful to him. As a result, various actions were taken and he no longer needed to have the heart surgery.

Charlie, a healthy man with a family history of colorectal cancer, wanted to see his genetic baseline and compare it with new scientific discoveries on a regular basis so he can take proactive actions regarding his health and wellness for the rest of his life. IWL is providing scientific consultation for him to understand various options for DNA screening and offered collaborative meeting with him and his physician to discuss current scientific discoveries and what can be shared under the current guidelines.

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Kris, a lung cancer patient, needed help in understanding the science involved in the application of personalized precision medicine pertaining to her non-small cell lung cancer. She was being treated with multiple drugs, including immunotherapy. She could not tolerate the various side effects resulting from the combined therapies. Among other side effects, she was dizzy all the time, did not have an appetite and could not taste anything that she was eating. IRIS met with the patient and her physician. We were able to explain the science involved and what newer drugs were available so she could make a better-informed decision. She made her choices, and she now has a higher quality of life and is able to eat, taste her food and has an appetite.

Steve, a pancreatic cancer patient came to us for help when his physician was about to recommend a different follow-on chemotherapy treatment because the previous treatment did not work. After IRIS carefully analyzed his medical records and interviewing him about his genetics, life style and history of supplements consumption, we were ready to present our scientific findings at a meeting with him and his physician. The physician told him at the meeting that he would die shortly because the disease had progressed too far. The patient died within a few days. He came to us too late. IRIS could have helped in offering advanced scientific knowledge for finding a targeted treatment for him if he came to us sooner.

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Joe and Cathy were concerned for their own health and a family member with autism spectrum disorder. Autism, a rare diagnosis only thirty years ago, now affects 1 out of 45 kids between the ages of 3 and 17. Autism is like an umbrella for many diseases. IRIS can help in better understanding which type of autism a person has so that the patient can get the right treatment. We can also conduct individualized clinical studies to potentially find what went wrong with the DNA instructions, and whether there is a way to improve the patient’s condition. We helped Joe and Cathy to better understand how the microbiome functionality, metabolite imbalances, DNA, and their life style work together to impact their health.  Cathy, after being diagnosed with a health disorder, came to IRIS to get a functional microbiome test so she can make better informed decisions.

Luke, a man with various diseases caused by inflammation, wanted help from IRIS to improve his health and wellness.  We reviewed the patient’s medical record and talked with the patient in detail about his life style, environment, and family medical history. We explained how the microbiome could impact his autoimmune disorders and how our in-depth metabolite test (chemical signatures) could be helpful to him. He had already gotten tested elsewhere (basic human DNA test, basic microbiome DNA test, allergy tests, and various blood tests), but those results did not help in resolving his conditions.  We uncovered this patient’s microbial function deficiency and are helping him to have a higher quality of life.

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Rhonda came to us when her mammogram showed that she might have breast cancer. She was scared, confused and did not know what to do. IRIS reviewed her medical records, family history, lifestyle, and environmental information. After further tests confirmed that she was positive for breast cancer, we reviewed the imaging and biopsy reports and explained the science involved and what she should expect so she can make better, well-informed decisions. We helped her as she went through the treatment process. She proceeded with confidence as an active participant in her care.

Tom, a man with heart disease, diabetes and depression, wanted to know how to improve his health and wellness.  IRIS explained the current scientific understanding behind each of his conditions, and how the microbiome could impact his health. He was also concerned about a family member, who was becoming obese. We discussed how obesity is linked to the microbiome and can lead to diabetes, heart disease, cancer, stroke, and other diseases.  IRIS can help in analyzing their DNA, RNA, functional microbiome, in-depth metabolites levels and lifestyle. We helped elucidate the root causes of obesity, and we help people to achieve lifelong fitness and wellness.

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